Anti-Human Glucagon R/GCGR Recombinant Antibody (SAA0132), APC (HW547137)

Name: Anti-Human Glucagon R/GCGR Recombinant Antibody (SAA0132), APC
Brand: abinScience
SKU: HW547137
Price: 290 USD
Availability: InStock

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概要
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参考文献
データシート
SDS

概要

カタログ番号	HW547137
種反応性	Human
アプリケーション	FCM
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgG2, kappa
クローンID	SAA0132
抱合	APC
ターゲット	GCGR, Glucagon receptor, GL-R
エンドトキシンレベル	Please contact with the lab for this information.
関連製品	Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10), APC
アクセッション番号	P47871
形態	Liquid
保存バッファー	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Glucagon receptor (GCGR) is a ~54 kDa protein. G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. 1. Qiao, A. et al. (2020) Science (New York, N.Y.) 367, 1346-1352. PMID: 32193322 2. Cong, Z. et al. (2024) Cell discovery 10, 18. PMID: 38346960
注意事項	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.