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Anti-Human GDF-11/BMP-11 Recombinant Antibody (SAA0430) (HF869107)

Anti-Human GDF-11/BMP-11 Recombinant Antibody (SAA0430)
Anti-Human GDF-11/BMP-11 Recombinant Antibody (SAA0430)
Precio(USD):
Especificación:
  • 50ug
  • 100ug
Número:
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  • Vista general

  • Imágenes

  • Referencias

  • Datasheet

  • SDS

Vista general
Número de catálogoHF869107
Reactividad de especiesHuman
AplicacionesELISA, FCM
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG2a, kappa
ID de clonSAA0430
Objetivo GDF11, BMP-11, BMP11, Growth/differentiation factor 11, GDF-11, Bone morphogenetic protein 11
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso O95390
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 0.09% Sodium azide.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

Growth/differentiation factor 11 (GDF11/BMP11) is a ~45 kDa protein. Secreted signal that acts globally to regulate anterior/posterior axial patterning during development. May play critical roles in patterning both mesodermal and neural tissues. It is required for proper vertebral patterning and orofacial development. Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3.

1. Cox, TC. et al. (2019) Human mutation 40, 1813-1825. PMID: 31215115
2. Walker, RG. et al. (2017) BMC biology 15, 19. PMID: 28257634
Nota For research use only.
Imágenes
  • Anti-Human GDF-11/BMP-11 Recombinant Antibody (SAA0430)

    SDS-PAGE

    SDS-PAGE for Anti-Human GDF11/BMP11 Antibody (SAA0430)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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