Anti-Human GFRA2 Polyclonal Antibody (HT422014)

Name: Anti-Human GFRA2 Polyclonal Antibody
Brand: abinScience
SKU: HT422014
Price: 168 USD
Availability: InStock

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50ug
100ug

Número:

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Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HT422014

Descripción

Anti-Human GFRA2 Polyclonal Antibody (HT422014) is a rabbit polyclonal antibody detecting GFRA2 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human GFRA2 (Asp226-Ser444).

Objetivo

TGF-beta-related neurotrophic factor receptor 2, RETL2, GDNFR-alpha-2, GFRA2, GFR-alpha-2, Neurturin receptor alpha, TRNR2, GDNF receptor beta, GDNF family receptor alpha-2, NRTNR-alpha, RET ligand 2, NTNR-alpha, GDNFRB, GDNF receptor alpha-2, GDNFR-beta

Purificación

Purified by antigen affinity column.

Número de acceso

O00451

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

GDNF family receptor alpha-2 (GFRA2) is a ~51 kDa protein. Receptor for neurturin (NRTN), a growth factor that supports the survival of sympathetic neurons. NRTN-binding leads to autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.

1. Cik, M. et al. (2000) The Journal of biological chemistry 275, 27505-12. PMID: 10829012

2. Sandmark, J. et al. (2018) The Journal of biological chemistry 293, 5492-5508. PMID: 29414779

3. Li, J. et al. (2019) eLife 8. PMID: 31535977

4. Baloh, RH. et al. (1997) Neuron 18, 793-802. PMID: 9182803

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-Human GFRA2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo