Anti-Human GFRA2 Polyclonal Antibody (HT422014)

Name: Anti-Human GFRA2 Polyclonal Antibody
Brand: abinScience
SKU: HT422014
Price: 168 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HT422014

Description

Anti-Human GFRA2 Polyclonal Antibody (HT422014) is a rabbit polyclonal antibody detecting GFRA2 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human GFRA2 (Asp226-Ser444).

Cible

TGF-beta-related neurotrophic factor receptor 2, RETL2, GDNFR-alpha-2, GFRA2, GFR-alpha-2, Neurturin receptor alpha, TRNR2, GDNF receptor beta, GDNF family receptor alpha-2, NRTNR-alpha, RET ligand 2, NTNR-alpha, GDNFRB, GDNF receptor alpha-2, GDNFR-beta

Purification

Purified by antigen affinity column.

Numéro d'accès

O00451

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

GDNF family receptor alpha-2 (GFRA2) is a ~51 kDa protein. Receptor for neurturin (NRTN), a growth factor that supports the survival of sympathetic neurons. NRTN-binding leads to autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.

1. Cik, M. et al. (2000) The Journal of biological chemistry 275, 27505-12. PMID: 10829012

2. Sandmark, J. et al. (2018) The Journal of biological chemistry 293, 5492-5508. PMID: 29414779

3. Li, J. et al. (2019) eLife 8. PMID: 31535977

4. Baloh, RH. et al. (1997) Neuron 18, 793-802. PMID: 9182803

Note

For research use only.

Images

Reférences

Fiche technique

Anti-Human GFRA2 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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