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Anti-Human GFR alpha ‑3/GDNF R alpha ‑3 Recombinant Antibody (SAA0178) (HT009107)

Anti-Human GFR alpha ‑3/GDNF R alpha ‑3 Recombinant Antibody (SAA0178)
Anti-Human GFR alpha ‑3/GDNF R alpha ‑3 Recombinant Antibody (SAA0178)
Precio(USD):
Especificación:
  • 50ug
  • 100ug
Número:
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  • Datasheet

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Vista general
Número de catálogoHT009107
Reactividad de especiesHuman
AplicacionesFCM
Especie huéspedHuman
ClonalidadMonoclonal
IsotipoIgG4, kappa
ID de clonSAA0178
Objetivo GFR-alpha-3, GDNF receptor alpha-3, GDNF family receptor alpha-3, GDNFR-alpha-3, GFRA3
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso O60609
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

GDNF family receptor alpha-3 (GFRA3) is a ~44 kDa protein. Receptor for artemin (ARTN), a growth factor that supports the survival of sensory and sympathetic peripheral neurons. ARTN-binding leads to autophosphorylation and activation of the RET receptor.

1. Li, J. et al. (2019) eLife 8. PMID: 31535977
2. Baloh, RH. et al. (1998) Neuron 21, 1291-302. PMID: 9883723
Nota For research use only.
Imágenes
  • Anti-Human GFR alpha ‑3/GDNF R alpha ‑3 Recombinant Antibody (SAA0178)

    Flow-cytometry

    Flow-cytometry using anti- human GFRA3 antibody.
    Human SH-SY5Y cell line were stained with an irrelevant antibody (Gray Histogram) or an anti- human GFRA3 antibody monoclonal antibody (Catalog # HT009107 , Red Histogram) at a concentration of 20 ug/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody (Catalog # HF690414) and cells analysed on a NovoCyte Flow Cytometer.

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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