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Anti-Human GINS2 Polyclonal Antibody (HP979014)

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Vista general
Número de catálogoHP979014
Descripción
Anti-Human GINS2 Polyclonal Antibody (HP979014) is a rabbit polyclonal antibody detecting GINS2 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human GINS2 (Met1-Phe185).
Objetivo GINS complex subunit 2, PSF2, DNA replication complex GINS protein PSF2, GINS2
Purificación Purified by antigen affinity column.
Número de acceso Q9Y248
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

DNA replication complex GINS protein PSF2 (GINS2) is a ~21 kDa protein. Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.

1. Kamada, K. et al. (2007) Nature structural & molecular biology 14, 388-96. PMID: 17417653
2. Rzechorzek, NJ. et al. (2020) Nucleic acids research 48, 6980-6995. PMID: 32453425
3. Jones, ML. et al. (2021) The EMBO journal 40, e108819. PMID: 34694004
4. Jenkyn-Bedford, M. et al. (2021) Nature 600, 743-747. PMID: 34700328
5. Baris, Y. et al. (2022) Nature 606, 204-210. PMID: 35585232
Nota For research use only.
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Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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