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| カタログ番号 | HP979014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human GINS2 Polyclonal Antibody (HP979014) is a rabbit polyclonal antibody detecting GINS2 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human GINS2 (Met1-Phe185). | ||||||||
| ターゲット | GINS complex subunit 2, PSF2, DNA replication complex GINS protein PSF2, GINS2 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9Y248 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | DNA replication complex GINS protein PSF2 (GINS2) is a ~21 kDa protein. Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. 1. Kamada, K. et al. (2007) Nature structural & molecular biology 14, 388-96. PMID: 17417653 2. Rzechorzek, NJ. et al. (2020) Nucleic acids research 48, 6980-6995. PMID: 32453425 3. Jones, ML. et al. (2021) The EMBO journal 40, e108819. PMID: 34694004 4. Jenkyn-Bedford, M. et al. (2021) Nature 600, 743-747. PMID: 34700328 5. Baris, Y. et al. (2022) Nature 606, 204-210. PMID: 35585232 | ||||||||
| 注意事項 | For research use only. |
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