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| カタログ番号 | HC529014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human GLO1 Polyclonal Antibody (HC529014) is a rabbit polyclonal antibody detecting GLO1 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human GLO1 (Gln33-Met184). | ||||||||
| ターゲット | Glyoxalase I, Glx I, Ketone-aldehyde mutase, GLO1, Lactoylglutathione lyase, Methylglyoxalase, S-D-lactoylglutathione methylglyoxal lyase, Aldoketomutase | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q04760 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Lactoylglutathione lyase (GLO1) is a ~20 kDa protein. Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B. Required for normal osteoclastogenesis. 1. Birkenmeier, G. et al. (2010) PloS one 5, e10399. PMID: 20454679 2. Chiba, T. et al. (2012) Bioorganic & medicinal chemistry letters 22, 7486-9. PMID: 23122816 3. Ridderström, M. et al. (1998) The Journal of biological chemistry 273, 21623-8. PMID: 9705294 4. de Hemptinne, V. et al. (2009) Molecular and cellular biochemistry 325, 169-78. PMID: 19199007 | ||||||||
| 注意事項 | For research use only. |
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