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Anti-Human GLRA1 Polyclonal Antibody (HB788014)

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Vista general
Número de catálogoHB788014
Descripción
Anti-Human GLRA1 Polyclonal Antibody (HB788014) is a rabbit polyclonal antibody detecting GLRA1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human GLRA1 (Ala32-Gln247).
Objetivo Glycine receptor 48 kDa subunit, Glycine receptor strychnine-binding subunit, Glycine receptor subunit alpha-1, GLRA1
Purificación Purified by antigen affinity column.
Número de acceso P23415
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Glycine receptor subunit alpha-1 (GLRA1) is a ~52 kDa protein. Subunit of heteromeric glycine-gated chloride channels. Plays an important role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents. Channel activity is potentiated by ethanol. Potentiation of channel activity by intoxicating levels of ethanol contribute to the sedative effects of ethanol.

1. Mohammadi, B. et al. (2003) European biophysics journal : EBJ 32, 529-36. PMID: 14551753
2. Mowrey, DD. et al. (2013) Structure (London, England : 1993) 21, 1897-904. PMID: 23994010
3. Moraga-Cid, G. et al. (2015) Proceedings of the National Academy of Sciences of the United States of America 112, 2865-70. PMID: 25730860
4. Liu, X. et al. (2023) Nature communications 14, 6377. PMID: 37821459
5. Shiang, R. et al. (1993) Nature genetics 5, 351-8. PMID: 8298642
6. Lynch, JW. et al. (1997) The EMBO journal 16, 110-20. PMID: 9009272
7. Zhang, Y. et al. (2015) Neuropharmacology 89, 391-7. PMID: 25445488
8. Horani, S. et al. (2015) Alcoholism, clinical and experimental research 39, 962-8. PMID: 25973519
Nota For research use only.
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Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human GLRA1 Polyclonal Antibody

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