Anti-Human GLRA1 Polyclonal Antibody (HB788014)

Name: Anti-Human GLRA1 Polyclonal Antibody
Brand: abinScience
SKU: HB788014
Price: 168 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HB788014

説明

Anti-Human GLRA1 Polyclonal Antibody (HB788014) is a rabbit polyclonal antibody detecting GLRA1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

種反応性

Human, Mouse, Rat

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human GLRA1 (Ala32-Gln247).

ターゲット

Glycine receptor 48 kDa subunit, Glycine receptor strychnine-binding subunit, Glycine receptor subunit alpha-1, GLRA1

精製

Purified by antigen affinity column.

アクセッション番号

P23415

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Glycine receptor subunit alpha-1 (GLRA1) is a ~52 kDa protein. Subunit of heteromeric glycine-gated chloride channels. Plays an important role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents. Channel activity is potentiated by ethanol. Potentiation of channel activity by intoxicating levels of ethanol contribute to the sedative effects of ethanol.

1. Mohammadi, B. et al. (2003) European biophysics journal : EBJ 32, 529-36. PMID: 14551753

2. Mowrey, DD. et al. (2013) Structure (London, England : 1993) 21, 1897-904. PMID: 23994010

3. Moraga-Cid, G. et al. (2015) Proceedings of the National Academy of Sciences of the United States of America 112, 2865-70. PMID: 25730860

4. Liu, X. et al. (2023) Nature communications 14, 6377. PMID: 37821459

5. Shiang, R. et al. (1993) Nature genetics 5, 351-8. PMID: 8298642

6. Lynch, JW. et al. (1997) The EMBO journal 16, 110-20. PMID: 9009272

7. Zhang, Y. et al. (2015) Neuropharmacology 89, 391-7. PMID: 25445488

8. Horani, S. et al. (2015) Alcoholism, clinical and experimental research 39, 962-8. PMID: 25973519

注意事項

For research use only.

イメージ

参考文献

データシート

Anti-Human GLRA1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-Human GLRA1 Polyclonal Antibody (HB788014)

概要

イメージ

参考文献

データシート

SDS