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| カタログ番号 | HA299023 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA, FCM, IHC | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | 5B8 | ||||
| ターゲット | MUC-4, Ascites sialoglycoprotein 1, Ascites sialoglycoprotein 2, ASGP-1, ASGP-2, Testis mucin, MUC4, Ascites sialoglycoprotein, Pancreatic adenocarcinoma mucin, ASGP, Tracheobronchial mucin, Mucin-4, glyco-MUC4 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q99102 | ||||
| RRID | Anti-Human glyco-MUC4 Antibody (5B8) (abinScience Cat# HA299023, RRID:AB_3727766) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Mucin-4 (glyco-MUC4) is a ~542 kDa protein. Membrane-bound mucin, a family of highly glycosylated proteins that constitute the major component of the mucus, the slimy and viscous secretion covering epithelial surfaces. These glycoproteins play important roles in the protection of the epithelium and are implicated in epithelial renewal and differentiation. Regulates cellular behavior through both anti-adhesive effects on cell-cell and cell-extracellular matrix interactions and its ability to act as an intramembrane ligand for ERBB2. Plays an important role in proliferation and differentiation of epithelial cells by inducing specific phosphorylation of ERBB2. In polarized epithelial cells, segregates ERBB2 and other ERBB receptors and prevents ERBB2 from acting as a coreceptor. 1. Moniaux, N. et al. (2000) European journal of biochemistry 267, 4536-44. PMID: 10880978 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human glyco-MUC4 Antibody (5B8)
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