Anti-Human GNAO1 Polyclonal Antibody (HY153014)

Name: Anti-Human GNAO1 Polyclonal Antibody
Brand: abinScience
SKU: HY153014
Price: 96 USD
Availability: InStock

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Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HY153014

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human GNAO1 (Met1-Tyr354).

Objetivo

Guanine nucleotide-binding protein G(o) subunit alpha, GNAO1

Purificación

Purified by antigen affinity column.

Número de acceso

P09471

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Guanine nucleotide-binding protein G(o) subunit alpha (GNAO1) is a ~40 kDa protein. Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins.

1. García-Nafría, J. et al. (2018) Nature 558, 620-623. PMID: 29925951

2. Ping, YQ. et al. (2021) Nature 589, 620-626. PMID: 33408414

Nota

For research use only.

Imágenes

Western blot

Western blot analysis was performed using anti-GNAO1 polyclonal antibody at 1μg/ml on various samples.
Lane 1: Mouse cerebellum lysate
Lane 2: Rat brain lysate
Lane 3: Rat cerebellum lysate

Referencias

Datasheet

Anti-Human GNAO1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo