Anti-Human GNAQ Polyclonal Antibody (HW752014)

Name: Anti-Human GNAQ Polyclonal Antibody
Brand: abinScience
SKU: HW752014
Price: 96 USD
Availability: InStock

Даташит Поделиться продуктом Копировать информацию

Цена(USD): --

Спецификация:

20ug
50ug
100ug

Количество:

Свяжитесь с нами

Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HW752014

Описание

Anti-Human GNAQ Polyclonal Antibody (HW752014) is a rabbit polyclonal antibody detecting GNAQ in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human GNAQ (Met1-Val359).

Цель

GNAQ, GAQ, Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein alpha-q

Очистка

Purified by antigen affinity column.

Номер доступа

P50148

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Guanine nucleotide-binding protein G(q) subunit alpha (GNAQ) is a ~42 kDa protein. Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins.

1. Zhang, X. et al. (2021) Nature chemical biology 17, 1230-1237. PMID: 34556863

2. Ding, Y. et al. (2022) Cell discovery 8, 55. PMID: 35672283

3. Falzone, ME. et al. (2023) Proceedings of the National Academy of Sciences of the United States of America 120, e2315011120. PMID: 37991948

4. Alvarez-Curto, E. et al. (2016) The Journal of biological chemistry 291, 27147-27159. PMID: 27852822

Примечание

For research use only.

Изображения

Western blot

Western blot analysis was performed using anti-GNAQ polyclonal antibody at 1μg/ml on various samples.
Lane 1: Jurkat cell lysate
Lane 2: Mouse brain lysate
Lane 3: Mouse cerebellum lysate
Lane 4: Mouse lung lysate
Lane 5: Rat brain lysate
Lane 6: Rat cerebellum lysate
Lane 7: Rat lung lysate

Ссылки

Даташит

Anti-Human GNAQ Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-Human GNAQ Polyclonal Antibody (HW752014)

Обзор

Изображения

Ссылки

Даташит

SDS