

| Numéro de catalogue | HY277014 | ||||||||
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| Description |
Anti-Human GNAT1 Polyclonal Antibody (HY277014) is a rabbit polyclonal antibody detecting GNAT1 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human GNAT1 (Met1-Phe350). | ||||||||
| Cible | Transducin alpha-1 chain, GNATR, Guanine nucleotide-binding protein G(t) subunit alpha-1, GNAT1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P11488 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Guanine nucleotide-binding protein G(t) subunit alpha-1 (GNAT1) is a ~40 kDa protein. Functions as a signal transducer for the rod photoreceptor RHO. Required for normal RHO-mediated light perception by the retina. Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs), such as the photoreceptor RHO. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Activated RHO promotes GDP release and GTP binding. 1. Naeem, MA. et al. (2012) Investigative ophthalmology & visual science 53, 1353-61. PMID: 22190596 | ||||||||
| Note | For research use only. |
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