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| カタログ番号 | HX006014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human GNG2 (Ala2-Leu71). | ||||||||
| ターゲット | GNG2, G gamma-I, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P59768 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 (GNG2) is a ~7 kDa protein. Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. 1. García-Nafría, J. et al. (2018) Nature 558, 620-623. PMID: 29925951 2. Xu, P. et al. (2021) Nature 592, 469-473. PMID: 33762731 3. Huang, S. et al. (2021) Cell research 31, 1036-1038. PMID: 34239069 4. Tan, Y. et al. (2022) Cell discovery 8, 50. PMID: 35610220 5. Huang, S. et al. (2022) Molecular cell 82, 2681-2695.e6. PMID: 35714614 6. Zhang, S. et al. (2022) Nature structural & molecular biology 29, 677-687. PMID: 35835867 7. Cao, C. et al. (2022) Neuron 110, 3154-3167.e7. PMID: 36087581 8. He, L. et al. (2023) Proceedings of the National Academy of Sciences of the United States of America 120, e2209917120. PMID: 36989299 9. Pei, Y. et al. (2023) Biochemical and biophysical research communications 671, 327-334. PMID: 37327704 10. Xu, Z. et al. (2023) Nature 624, 672-681. PMID: 37935376 | ||||||||
| 注意事項 | For research use only. |
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