

| Numéro de catalogue | HP568014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human GORASP2 Polyclonal Antibody (HP568014) is a rabbit polyclonal antibody detecting GORASP2 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human GORASP2 (Phe36-Glu208). | ||||||||
| Cible | GRS2, Golgi reassembly-stacking protein of 55 kDa, GOLPH6, p59, GORASP2, Golgi phosphoprotein 6, GRASP55, Golgi reassembly-stacking protein 2 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q9H8Y8 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Golgi reassembly-stacking protein 2 (GORASP2) is a ~47 kDa protein. Key structural protein of the Golgi apparatus. The membrane cisternae of the Golgi apparatus adhere to each other to form stacks, which are aligned side by side to form the Golgi ribbon. Acting in concert with GORASP1/GRASP65, is required for the formation and maintenance of the Golgi ribbon, and may be dispensable for the formation of stacks. However, other studies suggest that GORASP2 plays a role in the assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after breakdown during mitosis and meiosis. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA. 1. Zhang, Y. et al. (2021) The Journal of cell biology 220. PMID: 33301566 2. Shorter, J. et al. (1999) The EMBO journal 18, 4949-60. PMID: 10487747 3. Truschel, ST. et al. (2011) The Journal of biological chemistry 286, 20125-9. PMID: 21515684 4. Truschel, ST. et al. (2012) The Journal of biological chemistry 287, 19870-5. PMID: 22523075 5. Kuo, A. et al. (2000) The EMBO journal 19, 6427-39. PMID: 11101516 6. Gee, HY. et al. (2011) Cell 146, 746-60. PMID: 21884936 7. Kim, J. et al. (2016) Traffic (Copenhagen, Denmark) 17, 733-53. PMID: 27062250 8. Piao, H. et al. (2017) Scientific reports 7, 39887. PMID: 28067262 | ||||||||
| Note | For research use only. |
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