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Anti-Human GORASP2 Polyclonal Antibody (HP568014)

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Aperçu
Numéro de catalogueHP568014
Description
Anti-Human GORASP2 Polyclonal Antibody (HP568014) is a rabbit polyclonal antibody detecting GORASP2 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human GORASP2 (Phe36-Glu208).
Cible GRS2, Golgi reassembly-stacking protein of 55 kDa, GOLPH6, p59, GORASP2, Golgi phosphoprotein 6, GRASP55, Golgi reassembly-stacking protein 2
Purification Purified by antigen affinity column.
Numéro d'accès Q9H8Y8
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Golgi reassembly-stacking protein 2 (GORASP2) is a ~47 kDa protein. Key structural protein of the Golgi apparatus. The membrane cisternae of the Golgi apparatus adhere to each other to form stacks, which are aligned side by side to form the Golgi ribbon. Acting in concert with GORASP1/GRASP65, is required for the formation and maintenance of the Golgi ribbon, and may be dispensable for the formation of stacks. However, other studies suggest that GORASP2 plays a role in the assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after breakdown during mitosis and meiosis. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA.

1. Zhang, Y. et al. (2021) The Journal of cell biology 220. PMID: 33301566
2. Shorter, J. et al. (1999) The EMBO journal 18, 4949-60. PMID: 10487747
3. Truschel, ST. et al. (2011) The Journal of biological chemistry 286, 20125-9. PMID: 21515684
4. Truschel, ST. et al. (2012) The Journal of biological chemistry 287, 19870-5. PMID: 22523075
5. Kuo, A. et al. (2000) The EMBO journal 19, 6427-39. PMID: 11101516
6. Gee, HY. et al. (2011) Cell 146, 746-60. PMID: 21884936
7. Kim, J. et al. (2016) Traffic (Copenhagen, Denmark) 17, 733-53. PMID: 27062250
8. Piao, H. et al. (2017) Scientific reports 7, 39887. PMID: 28067262
Note For research use only.
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Formula
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