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| カタログ番号 | HP568014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human GORASP2 Polyclonal Antibody (HP568014) is a rabbit polyclonal antibody detecting GORASP2 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human GORASP2 (Phe36-Glu208). | ||||||||
| ターゲット | GRS2, Golgi reassembly-stacking protein of 55 kDa, GOLPH6, p59, GORASP2, Golgi phosphoprotein 6, GRASP55, Golgi reassembly-stacking protein 2 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9H8Y8 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Golgi reassembly-stacking protein 2 (GORASP2) is a ~47 kDa protein. Key structural protein of the Golgi apparatus. The membrane cisternae of the Golgi apparatus adhere to each other to form stacks, which are aligned side by side to form the Golgi ribbon. Acting in concert with GORASP1/GRASP65, is required for the formation and maintenance of the Golgi ribbon, and may be dispensable for the formation of stacks. However, other studies suggest that GORASP2 plays a role in the assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after breakdown during mitosis and meiosis. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA. 1. Zhang, Y. et al. (2021) The Journal of cell biology 220. PMID: 33301566 2. Shorter, J. et al. (1999) The EMBO journal 18, 4949-60. PMID: 10487747 3. Truschel, ST. et al. (2011) The Journal of biological chemistry 286, 20125-9. PMID: 21515684 4. Truschel, ST. et al. (2012) The Journal of biological chemistry 287, 19870-5. PMID: 22523075 5. Kuo, A. et al. (2000) The EMBO journal 19, 6427-39. PMID: 11101516 6. Gee, HY. et al. (2011) Cell 146, 746-60. PMID: 21884936 7. Kim, J. et al. (2016) Traffic (Copenhagen, Denmark) 17, 733-53. PMID: 27062250 8. Piao, H. et al. (2017) Scientific reports 7, 39887. PMID: 28067262 | ||||||||
| 注意事項 | For research use only. |
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