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Обзор
Каталожный номерHP568014
Описание
Anti-Human GORASP2 Polyclonal Antibody (HP568014) is a rabbit polyclonal antibody detecting GORASP2 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Реактивность видовHuman, Mouse, Rat
ПримененияELISA, IHC, WB
Хозяинский видRabbit
КлоональностьPolyclonal
ИзотипIgG
Иммуноген E. coli - derived recombinant Human GORASP2 (Phe36-Glu208).
Цель GRS2, Golgi reassembly-stacking protein of 55 kDa, GOLPH6, p59, GORASP2, Golgi phosphoprotein 6, GRASP55, Golgi reassembly-stacking protein 2
Очистка Purified by antigen affinity column.
Номер доступа Q9H8Y8
Форма Liquid
Буфер хранения 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта
Применение Разбавление
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон

Golgi reassembly-stacking protein 2 (GORASP2) is a ~47 kDa protein. Key structural protein of the Golgi apparatus. The membrane cisternae of the Golgi apparatus adhere to each other to form stacks, which are aligned side by side to form the Golgi ribbon. Acting in concert with GORASP1/GRASP65, is required for the formation and maintenance of the Golgi ribbon, and may be dispensable for the formation of stacks. However, other studies suggest that GORASP2 plays a role in the assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after breakdown during mitosis and meiosis. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA.

1. Zhang, Y. et al. (2021) The Journal of cell biology 220. PMID: 33301566
2. Shorter, J. et al. (1999) The EMBO journal 18, 4949-60. PMID: 10487747
3. Truschel, ST. et al. (2011) The Journal of biological chemistry 286, 20125-9. PMID: 21515684
4. Truschel, ST. et al. (2012) The Journal of biological chemistry 287, 19870-5. PMID: 22523075
5. Kuo, A. et al. (2000) The EMBO journal 19, 6427-39. PMID: 11101516
6. Gee, HY. et al. (2011) Cell 146, 746-60. PMID: 21884936
7. Kim, J. et al. (2016) Traffic (Copenhagen, Denmark) 17, 733-53. PMID: 27062250
8. Piao, H. et al. (2017) Scientific reports 7, 39887. PMID: 28067262
Примечание For research use only.
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Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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