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Anti-Human GPR15LG Polyclonal Antibody (HD559014)

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Vista general
Número de catálogoHD559014
Descripción
Anti-Human GPR15LG Polyclonal Antibody (HD559014) is a rabbit polyclonal antibody detecting Protein GPR15LG. Suitable for Human.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human GPR15LG (Lys25-Val82).
Objetivo AP-57, Antimicrobial peptide with 57 amino acid residues, Antimicrobial peptide-57, C10orf99, CSBF, Colon-derived SUSD2 binding factor, GPR15L, GPR15LG, Protein GPR15 ligand, Protein GPR15L, Protein GPR15LG, Secreted protein C10orf99
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso Q6UWK7
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

Protein GPR15LG is a ~9 kDa protein. Highly cationic protein that has multiple functions. Acts as a chemotactic factor that mediates lymphocytes recruitment to epithelia through binding and activation of the G-protein coupled receptor GPR15. May be a tumor suppressor; together with SUSD2 has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest. May regulate keratinocyte proliferation. In addition, through activation of Mas-related G protein-coupled receptors (MRGPRs) contributes to pruritogenesis by activating itch-selective sensory neurons and mast cells degranulation.

1. Suply, T. et al. (2017) Science signaling 10. PMID: 28900043
2. Ocón, B. et al. (2017) Frontiers in immunology 8, 1111. PMID: 28936214
3. Pan, W. et al. (2014) Scientific reports 4, 6812. PMID: 25351403
4. Chen, C. et al. (2018) Scientific reports 8, 8590. PMID: 29872130
5. Tseng, PY. et al. (2022) Science advances 8, eabm7342. PMID: 35704588
Nota For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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