Anti-Human GRB10 Polyclonal Antibody (HC527014)

Name: Anti-Human GRB10 Polyclonal Antibody
Brand: abinScience
SKU: HC527014
Price: 168 USD
Availability: InStock

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Especificación:

50ug
100ug

Número:

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Datasheet
SDS

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Número de catálogo

HC527014

Descripción

Anti-Human GRB10 Polyclonal Antibody (HC527014) is a rabbit polyclonal antibody detecting GRB10. Suitable for Human.

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human GRB10 (Lys167-Leu417).

Objetivo

GRB10, GRB10 adapter protein, GRBIR, Growth factor receptor-bound protein 10, Insulin receptor-binding protein Grb-IR, KIAA0207

Nivel de endotoxinas

Please contact with the lab for this information.

Purificación

Purified by antigen affinity column.

Número de acceso

Q13322

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Fondo

Growth factor receptor-bound protein 10 (GRB10) is a ~67 kDa protein. Adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. Binds to, and suppress signals from, activated receptors tyrosine kinases, including the insulin (INSR) and insulin-like growth factor (IGF1R) receptors. The inhibitory effect can be achieved by 2 mechanisms: interference with the signaling pathway and increased receptor degradation. Delays and reduces AKT1 phosphorylation in response to insulin stimulation. Blocks association between INSR and IRS1 and IRS2 and prevents insulin-stimulated IRS1 and IRS2 tyrosine phosphorylation.

Nota

For research use only

Imágenes

Referencias

Datasheet

Anti-Human GRB10 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo

Anti-Human GRB10 Polyclonal Antibody (HC527014)

Vista general

Imágenes

Referencias

Datasheet

SDS