

| Número de catálogo | HT246013 | ||||
|---|---|---|---|---|---|
| Descripción |
Anti-Human GREM1 Recombinant Antibody (Ab7326) (HT246013) is a mouse monoclonal antibody detecting GREM1 in ELISA, Functional assay. Suitable for Human, Mouse.
Highlights
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| Reactividad de especies | Human, Mouse | ||||
| Aplicaciones | ELISA, Functional assay | ||||
| Especie huésped | Mouse | ||||
| Clonalidad | Monoclonal | ||||
| Isotipo | IgG1 | ||||
| ID de clon | Ab7326 | ||||
| Objetivo | CKTSF1B1, Cell proliferation-inducing gene 2 protein, Cysteine knot superfamily 1, BMP antagonist 1, DAN domain family member 2, DAND2, DRM, Down-regulated in Mos-transformed cells protein, GREM1, Gremlin-1, IHG-2, Increased in high glucose protein 2 | ||||
| Nivel de endotoxinas | < 10 EU/mg as determined by LAL method. | ||||
| Pureza | >95% as determined by SDS-PAGE. | ||||
| Purificación | Protein A/G purified from cell culture supernatant. | ||||
| Número de acceso | O60565 | ||||
| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Fondo | Gremlin-1 (GREM1) is a ~20 kDa protein. Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner. Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro). Acts as inhibitor of monocyte chemotaxis. Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed. 1. Kišonaitė, M. et al. (2016) The Biochemical journal 473, 1593-604. PMID: 27036124 | ||||
| Nota | For research use only. | ||||
| Isotype Control | Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207) |

SDS-PAGE for Anti-Human GREM1 Antibody (Ab7326)




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