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Anti-Human GREM1 Recombinant Antibody (SAA2524) (MT246013)

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Anti-Human GREM1 Recombinant Antibody (SAA2524)
Anti-Human GREM1 Recombinant Antibody (SAA2524)
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  • 100ug
  • 1mg
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Vista general
Número de catálogoMT246013
Descripción
Anti-Human GREM1 Recombinant Antibody (SAA2524) (MT246013) is a mouse monoclonal antibody detecting GREM1 in ELISA, FCM, Functional assay. Suitable for Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesMouse
AplicacionesELISA, FCM, Functional assay
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG1
ID de clonSAA2524
Objetivo Cktsf1b1, Cysteine knot superfamily 1, BMP antagonist 1, Down-regulated in Mos-transformed cells protein, Drm, Grem1, Gremlin-1
Nivel de endotoxinas < 10 EU/mg as determined by LAL method.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso O70326
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:2000-1:20000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Gremlin-1 (GREM1) is a ~20 kDa protein. Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as BMP a antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner. Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro). Acts as inhibitor of monocyte chemotaxis.

1. Khokha, MK. et al. (2003) Nature genetics 34, 303-7. PMID: 12808456
2. Michos, O. et al. (2004) Development (Cambridge, England) 131, 3401-10. PMID: 15201225
3. Pangas, SA. et al. (2004) The Journal of biological chemistry 279, 32281-6. PMID: 15133038
Nota For research use only.
Isotype Control Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207)
Imágenes
  • Anti-Human GREM1 Recombinant Antibody (SAA2524)

    SDS-PAGE

    SDS-PAGE for Anti-Human GREM1 Antibody (SAA2524)

Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human GREM1 Recombinant Antibody (SAA2524)

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