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| カタログ番号 | MT246013 | ||||
|---|---|---|---|---|---|
| 説明 |
Anti-Human GREM1 Recombinant Antibody (SAA2524) (MT246013) is a mouse monoclonal antibody detecting GREM1 in ELISA, FCM, Functional assay. Suitable for Mouse.
Highlights
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| 種反応性 | Mouse | ||||
| アプリケーション | ELISA, FCM, Functional assay | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG1 | ||||
| クローンID | SAA2524 | ||||
| ターゲット | Cktsf1b1, Cysteine knot superfamily 1, BMP antagonist 1, Down-regulated in Mos-transformed cells protein, Drm, Grem1, Gremlin-1 | ||||
| エンドトキシンレベル | < 10 EU/mg as determined by LAL method. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | O70326 | ||||
| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Gremlin-1 (GREM1) is a ~20 kDa protein. Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as BMP a antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner. Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro). Acts as inhibitor of monocyte chemotaxis. 1. Khokha, MK. et al. (2003) Nature genetics 34, 303-7. PMID: 12808456 2. Michos, O. et al. (2004) Development (Cambridge, England) 131, 3401-10. PMID: 15201225 3. Pangas, SA. et al. (2004) The Journal of biological chemistry 279, 32281-6. PMID: 15133038 | ||||
| 注意事項 | For research use only. | ||||
| Isotype Control | Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207) |
SDS-PAGE for Anti-Human GREM1 Antibody (SAA2524)
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