Anti-Human GSDME Polyclonal Antibody (HT311014)

Name: Anti-Human GSDME Polyclonal Antibody
Brand: abinScience
SKU: HT311014
Price: 168 USD
Availability: InStock

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Especificación:

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Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HT311014

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human GSDME (Met1-Cys235).

Objetivo

ICERE-1, ICERE1, GSDME-CT, GSDME-NT, DFNA5, Inversely correlated with estrogen receptor expression 1, Gasdermin-E, GSDME, Non-syndromic hearing impairment protein 5

Purificación

Purified by antigen affinity column.

Número de acceso

O60443

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Gasdermin-E (GSDME) is a ~54 kDa protein. Precursor of a pore-forming protein that converts non-inflammatory apoptosis to pyroptosis. This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-E, N-terminal) binds to membranes and forms pores, triggering pyroptosis.

1. Ding, J. et al. (2016) Nature 535, 111-6. PMID: 27281216

2. Wang, Y. et al. (2017) Nature 547, 99-103. PMID: 28459430

3. Zhou, B. et al. (2021) Cell reports 35, 108998. PMID: 33852854

4. Planès, R. et al. (2022) Molecular cell 82, 2385-2400.e9. PMID: 35594856

5. Ren, Y. et al. (2023) Cancer research 83, 1074-1093. PMID: 36607699

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-Human GSDME Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo