Anti-Human HCN2 Polyclonal Antibody (HP198014)

Name: Anti-Human HCN2 Polyclonal Antibody
Brand: abinScience
SKU: HP198014
Price: 168 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HP198014

Description

Anti-Human HCN2 Polyclonal Antibody (HP198014) is a rabbit polyclonal antibody detecting HCN2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human HCN2 (Gly524-Leu713).

Cible

HCN2, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2, BCNG-2, Brain cyclic nucleotide-gated channel 2, BCNG2

Purification

Purified by antigen affinity column.

Numéro d'accès

Q9UL51

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (HCN2) is a ~96 kDa protein. Hyperpolarization-activated ion channel that is permeable to sodium and potassium ions. Displays lower selectivity for K(+) over Na(+) ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Can also transport ammonium in the distal nephron. Involved in the initiation of neuropathic pain in sensory neurons.

1. Ludwig, A. et al. (1999) The EMBO journal 18, 2323-9. PMID: 10228147

2. Lolicato, M. et al. (2011) The Journal of biological chemistry 286, 44811-20. PMID: 22006928

3. Vaccari, T. et al. (1999) Biochimica et biophysica acta 1446, 419-25. PMID: 10524219

Note

For research use only.

Images

Reférences

Fiche technique

Anti-Human HCN2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-Human HCN2 Polyclonal Antibody (HP198014)

Aperçu

Images

Reférences

Fiche technique

SDS