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| カタログ番号 | HP198014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human HCN2 Polyclonal Antibody (HP198014) is a rabbit polyclonal antibody detecting HCN2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human HCN2 (Gly524-Leu713). | ||||||||
| ターゲット | HCN2, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2, BCNG-2, Brain cyclic nucleotide-gated channel 2, BCNG2 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9UL51 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (HCN2) is a ~96 kDa protein. Hyperpolarization-activated ion channel that is permeable to sodium and potassium ions. Displays lower selectivity for K(+) over Na(+) ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Can also transport ammonium in the distal nephron. Involved in the initiation of neuropathic pain in sensory neurons. 1. Ludwig, A. et al. (1999) The EMBO journal 18, 2323-9. PMID: 10228147 2. Lolicato, M. et al. (2011) The Journal of biological chemistry 286, 44811-20. PMID: 22006928 3. Vaccari, T. et al. (1999) Biochimica et biophysica acta 1446, 419-25. PMID: 10524219 | ||||||||
| 注意事項 | For research use only. |
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