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Anti-Human HDAC7 Polyclonal Antibody (HV082014)

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Vista general
Número de catálogoHV082014
Descripción
Anti-Human HDAC7 Polyclonal Antibody (HV082014) is a rabbit polyclonal antibody detecting HDAC7. Suitable for Mouse and Human.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human HDAC7 (Ser482-Ser903).
Objetivo EC:3.5.1.-, EC:3.5.1.98, HD7, HD7a, HDAC7, HDAC7A, Histone deacetylase 7, Histone deacetylase 7A, Protein deacetylase HDAC7
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso Q8WUI4
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

Histone deacetylase 7 (HDAC7) is a ~102 kDa protein. Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors.

1. Bryant, H. et al. (2002) Journal of virology 76, 10290-8. PMID: 12239305
2. Li, B. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 4571-6. PMID: 17360565
3. Lee, DY. et al. (2017) Proceedings of the National Academy of Sciences of the United States of America 114, 2072-2077. PMID: 28167758
4. Zhang, XL. et al. (2023) Nature communications 14, 3815. PMID: 37369679
Nota For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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