Anti-Human HDAC7 Polyclonal Antibody (HV082014)

Name: Anti-Human HDAC7 Polyclonal Antibody
Brand: abinScience
SKU: HV082014
Price: 168 USD
Availability: InStock

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Spécification :

50ug
100ug

Nombre :

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SDS

Aperçu

Numéro de catalogue

HV082014

Description

Anti-Human HDAC7 Polyclonal Antibody (HV082014) is a rabbit polyclonal antibody detecting HDAC7. Suitable for Mouse and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human HDAC7 (Ser482-Ser903).

Cible

EC:3.5.1.-, EC:3.5.1.98, HD7, HD7a, HDAC7, HDAC7A, Histone deacetylase 7, Histone deacetylase 7A, Protein deacetylase HDAC7

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

Q8WUI4

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Contexte

Histone deacetylase 7 (HDAC7) is a ~102 kDa protein. Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors.

1. Bryant, H. et al. (2002) Journal of virology 76, 10290-8. PMID: 12239305

2. Li, B. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 4571-6. PMID: 17360565

3. Lee, DY. et al. (2017) Proceedings of the National Academy of Sciences of the United States of America 114, 2072-2077. PMID: 28167758

4. Zhang, XL. et al. (2023) Nature communications 14, 3815. PMID: 37369679

Note

For research use only

Images

Reférences

Fiche technique

Anti-Human HDAC7 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-Human HDAC7 Polyclonal Antibody (HV082014)

Aperçu

Images

Reférences

Fiche technique

SDS