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| カタログ番号 | HV082014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human HDAC7 Polyclonal Antibody (HV082014) is a rabbit polyclonal antibody detecting HDAC7. Suitable for Mouse and Human.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human HDAC7 (Ser482-Ser903). | ||||||||
| ターゲット | EC:3.5.1.-, EC:3.5.1.98, HD7, HD7a, HDAC7, HDAC7A, Histone deacetylase 7, Histone deacetylase 7A, Protein deacetylase HDAC7 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q8WUI4 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 背景 | Histone deacetylase 7 (HDAC7) is a ~102 kDa protein. Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. 1. Bryant, H. et al. (2002) Journal of virology 76, 10290-8. PMID: 12239305 2. Li, B. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 4571-6. PMID: 17360565 3. Lee, DY. et al. (2017) Proceedings of the National Academy of Sciences of the United States of America 114, 2072-2077. PMID: 28167758 4. Zhang, XL. et al. (2023) Nature communications 14, 3815. PMID: 37369679 | ||||||||
| 注意事項 | For research use only |
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