Anti-Human HDGFL2 Recombinant Nanobody (SAA2783) (HA200013)

Name: Anti-Human HDGFL2 Recombinant Nanobody (SAA2783)
Brand: abinScience
SKU: HA200013
Price: 191 USD
Availability: InStock

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50ug
100ug
1mg

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Каталожный номер	HA200013
Описание	Anti-Human HDGFL2 Nanobody (SAA2783) (HA200013) is a alpaca monoclonal antibody detecting HDGFL2. Suitable for Human.
Реактивность видов	Human
Применения	ELISA
Хозяинский вид	Alpaca
Клоональность	Monoclonal
Изотип	VHH-His
ID клона	SAA2783
Цель	HDGF-2, HDGF-related protein 2, HDGF2, HDGFL2, HDGFRP2, HRP-2, HRP2, Hepatoma-derived growth factor 2, Hepatoma-derived growth factor-related protein 2
Уровень эндотоксинов	< 10 EU/mg as determined by LAL method.
Чистота	>95% as determined by SDS-PAGE.
Очистка	Purified by Nickel column.
Номер доступа	Q7Z4V5
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Реконституция	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон	Hepatoma-derived growth factor-related protein 2 (HDGFL2) is a ~74 kDa protein. Acts as an epigenetic regulator of myogenesis in cooperation with DPF3a (isoform 2 of DPF3/BAF45C). Associates with the BAF complex via its interaction with DPF3a and HDGFL2-DPF3a activate myogenic genes by increasing chromatin accessibility through recruitment of SMARCA4/BRG1/BAF190A (ATPase subunit of the BAF complex) to myogenic gene promoters. Promotes the repair of DNA double-strand breaks (DSBs) through the homologous recombination pathway by facilitating the recruitment of the DNA endonuclease RBBP8 to the DSBs. Preferentially binds to chromatin regions marked by H3K9me3, H3K27me3 and H3K36me2. Involved in cellular growth control, through the regulation of cyclin D1 expression. 1. Zhu, X. et al. (2020) Nucleic acids research 48, 6563-6582. PMID: 32459350 2. Baude, A. et al. (2016) Nucleic acids research 44, 2214-26. PMID: 26721387 3. Gao, K. et al. (2015) Biochemical and biophysical research communications 458, 849-55. PMID: 25689719
Примечание	For research use only.

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Anti-Human HDGFL2 Recombinant Nanobody (SAA2783).pdf

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Anti-Human HDGFL2 Recombinant Nanobody (SAA2783) (HA200013)

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