

| カタログ番号 | HC651014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human HERPUD1 Polyclonal Antibody (HC651014) is a rabbit polyclonal antibody detecting HERPUD1 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human HERPUD1 (Glu8-Asn87). | ||||||||
| ターゲット | HERPUD1, HERP, Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein, MIF1, KIAA0025, Methyl methanesulfonate (MMF)-inducible fragment protein 1 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q15011 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein (HERPUD1) is a ~43 kDa protein. Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Could enhance presenilin-mediated amyloid-beta protein 40 generation. Binds to ubiquilins and this interaction is required for efficient degradation of CD3D via the ERAD pathway. 1. Schulze, A. et al. (2005) Journal of molecular biology 354, 1021-7. PMID: 16289116 2. Schulz, J. et al. (2017) Journal of cell science 130, 3322-3335. PMID: 28827405 3. Kim, TY. et al. (2008) Biochemical and biophysical research communications 369, 741-6. PMID: 18307982 | ||||||||
| 注意事項 | For research use only. |
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