

| Numéro de catalogue | HA490014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human HPS4 Polyclonal Antibody (HA490014) is a rabbit polyclonal antibody detecting HPS4 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human HPS4 (Ser13-His216). | ||||||||
| Cible | HPS4 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q9NQG7 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Noms alternatifs | BLOC-3 complex member HPS4, Hermansky-Pudlak syndrome 4 protein, Light-ear protein homolog, HPS4 | ||||||||
| Contexte | BLOC-3 complex member HPS4 is a ~76 kDa protein. Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form. The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38. 1. Gerondopoulos, A. et al. (2012) Current biology : CB 22, 2135-9. PMID: 23084991 | ||||||||
| Note | For research use only. |
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