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| カタログ番号 | HP841014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human HPS6 Polyclonal Antibody (HP841014) is a rabbit polyclonal antibody detecting HPS6 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human HPS6 (Thr371-Met454). | ||||||||
| ターゲット | Ruby-eye protein homolog, HPS6, Ru, Hermansky-Pudlak syndrome 6 protein | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q86YV9 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | BLOC-2 complex member HPS6 is a ~82 kDa protein. May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Acts as a cargo adapter for the dynein-dynactin motor complex to mediate the transport of lysosomes from the cell periphery to the perinuclear region. Facilitates retrograde lysosomal trafficking by linking the motor complex to lysosomes, and perinuclear positioning of lysosomes is crucial for the delivery of endocytic cargos to lysosomes, for lysosome maturation and functioning. 1. Schreyer-Shafir, N. et al. (2006) Human mutation 27, 1158. PMID: 17041891 2. Li, K. et al. (2014) Journal of cell science 127, 4574-88. PMID: 25189619 | ||||||||
| 注意事項 | For research use only. |
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