

| Numéro de catalogue | HB040014 | ||||||||
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| Description |
Anti-Human HSPA6 Polyclonal Antibody (HB040014) is a rabbit polyclonal antibody detecting HSPA6 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human HSPA6 (Met1-Cys387). | ||||||||
| Cible | HSP70B', HSPA6, Heat shock 70 kDa protein B', Heat shock 70 kDa protein 6 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P17066 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Heat shock 70 kDa protein 6 (HSPA6) is a ~71 kDa protein. Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. 1. Radons, J. (2016) Cell stress & chaperones 21, 379-404. PMID: 26865365 | ||||||||
| Note | For research use only. |
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