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| カタログ番号 | HW325014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human HTR7 Polyclonal Antibody (HW325014) is a rabbit polyclonal antibody detecting HTR7 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human HTR7 (Met258-Ala325). | ||||||||
| ターゲット | 5-hydroxytryptamine receptor 7, 5-HT-X, HTR7, 5-HT7, Serotonin receptor 7, 5-HT-7 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P34969 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | 5-hydroxytryptamine receptor 7 (HTR7) is a ~53 kDa protein. G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR7 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity. 1. Huang, S. et al. (2022) Molecular cell 82, 2681-2695.e6. PMID: 35714614 2. Bard, JA. et al. (1993) The Journal of biological chemistry 268, 23422-6. PMID: 8226867 | ||||||||
| 注意事項 | For research use only. |
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