Anti-Human HTRA3 Polyclonal Antibody (HX117014)

Name: Anti-Human HTRA3 Polyclonal Antibody
Brand: abinScience
SKU: HX117014
Price: 168 USD
Availability: InStock

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Spécification :

50ug
100ug

Nombre :

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SDS

Aperçu

Numéro de catalogue

HX117014

Description

Anti-Human HTRA3 Polyclonal Antibody (HX117014) is a rabbit polyclonal antibody detecting HTRA3. Suitable for Mouse, Human, and Rat.

Highlights

●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human HTRA3 (Asn141-Pro333).

Cible

EC:3.4.21.-, HTRA3, High-temperature requirement factor A3, PRSP, Pregnancy-related serine protease, Serine protease HTRA3

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

P83110

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Contexte

Serine protease HTRA3 is a ~48 kDa protein. Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans. May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization.

1. Singh, H. et al. (2011) Human reproduction (Oxford, England) 26, 748-57. PMID: 21321049

2. Singh, H. et al. (2012) BioTechniques 52, 23-8. PMID: 22229724

Note

For research use only

Images

Reférences

Fiche technique

Anti-Human HTRA3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-Human HTRA3 Polyclonal Antibody (HX117014)

Aperçu

Images

Reférences

Fiche technique

SDS