

| Número de catálogo | HY419014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human IAPP Polyclonal Antibody (HY419014) is a rabbit polyclonal antibody detecting IAPP in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human IAPP (Thr23-Leu89). | ||||||||
| Objetivo | IAPP, Islet amyloid polypeptide, Diabetes-associated peptide, Insulinoma amyloid peptide, Amylin, DAP | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P10997 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Islet amyloid polypeptide (IAPP) is a ~9 kDa protein. Amylin/IAPP is a glucoregulatory peptide hormone that plays an important role in the regulation of energy homeostasis. Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. IAPP function is mediated by the CALCR-RAMPs (AMYRs) receptor complexes. Amylin can also bind CALCR receptor in the absence of RAMPs, although it is more selective for AMYRs. 1. Roberts, AN. et al. (1989) Proceedings of the National Academy of Sciences of the United States of America 86, 9662-6. PMID: 2690069 | ||||||||
| Nota | For research use only. |




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