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| カタログ番号 | HF781033 | ||||||
|---|---|---|---|---|---|---|---|
| 種反応性 | Human | ||||||
| アプリケーション | ELISA, IHC, WB | ||||||
| 宿主種 | Mouse | ||||||
| クローン性 | Monoclonal | ||||||
| アイソタイプ | IgG2a, kappa | ||||||
| クローンID | LMab-1 | ||||||
| ターゲット | IDH1, IDH, NADP(+)-specific ICDH, Isocitrate dehydrogenase [NADP] cytoplasmic, PICD, IDP, Cytosolic NADP-isocitrate dehydrogenase, Oxalosuccinate decarboxylase | ||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||
| 純度 | >95% as determined by SDS-PAGE. | ||||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||||
| アクセッション番号 | O75874 | ||||||
| RRID | Anti-Human IDH1-R132L-specific Antibody (LMab-1) (abinScience Cat# HF781033, RRID:AB_3729710) |
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| 形態 | Liquid | ||||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||||
| 背景 | Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1-R132L-specific) is a ~46 kDa protein. Catalyzes the NADP(+)-dependent oxidative decarboxylation of isocitrate (D-threo-isocitrate) to 2-ketoglutarate (2-oxoglutarate), which is required by other enzymes such as the phytanoyl-CoA dioxygenase. Plays a critical role in the generation of NADPH, an important cofactor in many biosynthesis pathways. May act as a corneal epithelial crystallin and may be involved in maintaining corneal epithelial transparency. 1. Geisbrecht, BV. et al. (1999) The Journal of biological chemistry 274, 30527-33. PMID: 10521434 2. Dang, L. et al. (2009) Nature 462, 739-44. PMID: 19935646 | ||||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human IDH1-R132L-specific Antibody (LMab-1)
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
