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| カタログ番号 | HY160014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human IFIT2 Polyclonal Antibody (HY160014) is a rabbit polyclonal antibody detecting IFIT2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human IFIT2 (Met1-Glu472). | ||||||||
| ターゲット | P54, Interferon-induced 54 kDa protein, Interferon-induced protein with tetratricopeptide repeats 2, CIG-42, G10P2, IFI54, IFIT-2, IFI-54K, ISG-54 K, IFIT2, ISG54 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P09913 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Interferon-induced protein with tetratricopeptide repeats 2 (IFIT2) is a ~54 kDa protein. IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis. | ||||||||
| 注意事項 | For research use only. |
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