Anti-Human IFIT5 Polyclonal Antibody (HC576014)

Name: Anti-Human IFIT5 Polyclonal Antibody
Brand: abinScience
SKU: HC576014
Price: 168 USD
Availability: InStock

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Especificación:

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Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HC576014

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human IFIT5 (Met1-Ile482).

Objetivo

ISG58, RI58, IFIT-5, P58, Interferon-induced protein with tetratricopeptide repeats 5, IFIT5, Retinoic acid- and interferon-inducible 58 kDa protein, Interferon-induced 58 kDa protein

Purificación

Purified by antigen affinity column.

Número de acceso

Q13325

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Interferon-induced protein with tetratricopeptide repeats 5 (IFIT5) is a ~55 kDa protein. Interferon-induced RNA-binding protein involved in the human innate immune response. Has a broad and adaptable RNA structure recognition important for RNA recognition specificity in antiviral defense. Binds precursor and processed tRNAs as well as poly-U-tailed tRNA fragments. Specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection.

1. Katibah, GE. et al. (2013) Molecular cell 49, 743-50. PMID: 23317505

2. Feng, F. et al. (2013) Cell research 23, 1055-8. PMID: 23774268

3. Katibah, GE. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, 12025-30. PMID: 25092312

4. Abbas, YM. et al. (2013) Nature 494, 60-4. PMID: 23334420

5. Zheng, C. et al. (2015) Cellular signalling 27, 2343-54. PMID: 26334375

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-Human IFIT5 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo