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Anti-Human IFITM1 Polyclonal Antibody (HC024014)

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Anti-Human IFITM1 Polyclonal Antibody
Anti-Human IFITM1 Polyclonal Antibody
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Aperçu
Numéro de catalogueHC024014
Description
Anti-Human IFITM1 Polyclonal Antibody (HC024014) is a rabbit polyclonal antibody detecting Interferon-induced transmembrane protein 1; Dispanin subfamily A member 2a; DSPA2a; Interferon-induced protein 17; Interferon-inducible protein 9-27; Leu-13 antigen; CD225; IFITM1; CD225; IFI17 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactivité des espècesHuman
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant human IFITM1 (His2-His36&Ala58-Asn86&Ser108-Tyr125).
Cible Interferon-induced transmembrane protein 1; Dispanin subfamily A member 2a; DSPA2a; Interferon-induced protein 17; Interferon-inducible protein 9-27; Leu-13 antigen; CD225; IFITM1; CD225; IFI17
Niveau d'endotoxines Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Numéro d'accès P13164
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Interferon-induced transmembrane protein 1 (IFITM1) is a ~13 kDa protein. IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronaviruses (SARS-CoV and SARS-CoV-2), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV and SARS-CoV-2 S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Inhibits SARS-CoV-2 S protein-mediated syncytia formation.

1. Narayana, SK. et al. (2015) The Journal of biological chemistry 290, 25946-59. PMID: 26354436
2. Shi, G. et al. (2021) The EMBO journal 40, e106501. PMID: 33270927
3. Buchrieser, J. et al. (2020) The EMBO journal 39, e106267. PMID: 33051876
Note For research use only
Images
  • Anti-Human IFITM1 Polyclonal Antibody

    Western blot

    Lane 1: Jurkat cell lysate
    Lane 2: HepG2 cell lysate
    Lane 3: K562 cell lysate
    Lane 4: HL-60 cell lysate
    Lane 5: Hela cell lysate
    Lane 6: 293T cell lysate
    Lane 7: NIH3T3 cell lysate
    Lane 8: MCF-7 cell lysate
    Lane 9: Mouse spleen lysate
    Lane 10: Mouse testis lysate
    Lane11: Mouse brain lysate
    Lane12: Rat spleen lysate
    Lane13: Rat testis lysate
    Lane14: Rat brain lysate

Reférences
Fiche technique
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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