

| Número de catálogo | HP637014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human IFT140 Polyclonal Antibody (HP637014) is a rabbit polyclonal antibody detecting IFT140 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human IFT140 (Met1-Ser410). | ||||||||
| Objetivo | Intraflagellar transport protein 140 homolog, WDTC2, KIAA0590, IFT140, WD and tetratricopeptide repeats protein 2 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q96RY7 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Intraflagellar transport protein 140 homolog (IFT140) is a ~165 kDa protein. Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs). Plays a pivotal role in proper development and function of ciliated cells through its role in ciliogenesis and/or cilium maintenance. Required for the development and maintenance of the outer segments of rod and cone photoreceptor cells. Plays a role in maintenance and the delivery of opsin to the outer segment of photoreceptor cells. 1. Mukhopadhyay, S. et al. (2010) Genes & development 24, 2180-93. PMID: 20889716 2. Perrault, I. et al. (2012) American journal of human genetics 90, 864-70. PMID: 22503633 | ||||||||
| Nota | For research use only. |
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