

| Numéro de catalogue | HP637014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human IFT140 Polyclonal Antibody (HP637014) is a rabbit polyclonal antibody detecting IFT140 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human IFT140 (Met1-Ser410). | ||||||||
| Cible | Intraflagellar transport protein 140 homolog, WDTC2, KIAA0590, IFT140, WD and tetratricopeptide repeats protein 2 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q96RY7 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Intraflagellar transport protein 140 homolog (IFT140) is a ~165 kDa protein. Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs). Plays a pivotal role in proper development and function of ciliated cells through its role in ciliogenesis and/or cilium maintenance. Required for the development and maintenance of the outer segments of rod and cone photoreceptor cells. Plays a role in maintenance and the delivery of opsin to the outer segment of photoreceptor cells. 1. Mukhopadhyay, S. et al. (2010) Genes & development 24, 2180-93. PMID: 20889716 2. Perrault, I. et al. (2012) American journal of human genetics 90, 864-70. PMID: 22503633 | ||||||||
| Note | For research use only. |
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