Anti-Human IL-13 Recombinant Antibody (SAA2016) (HW632013)

Name: Anti-Human IL-13 Recombinant Antibody (SAA2016)
Brand: abinScience
SKU: HW632013
Price: 110 USD
Availability: InStock

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Precio(USD):

Especificación:

20ug
50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HW632013

Reactividad de especies

Human

Aplicaciones

ELISA, WB

Especie huésped

Human

Clonalidad

Monoclonal

Isotipo

IgG4, kappa

ID de clon

SAA2016

Aplicaciones probadas

Objetivo

IL-13, IL13, Interleukin-13, NC30

Nivel de endotoxinas

< 10 EU/mg

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

P35225

RRID

Anti-Human IL13 Antibody (SAA2016) (abinScience Cat# HW632013, RRID:AB_3727928)
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Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Interleukin-13 (IL13) is a ~15 kDa protein. Cytokine that plays important roles in allergic inflammation and immune response to parasite infection. Synergizes with IL2 in regulating interferon-gamma synthesis. Stimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells. Plays an important role in controlling IL33 activity by modulating the production of transmembrane and soluble forms of interleukin-1 receptor-like 1/IL1RL1. Displays the capacity to antagonize Th1-driven proinflammatory immune response and downregulates synthesis of many proinflammatory cytokines including IL1, IL6, IL10, IL12 and TNF through a mechanism that partially involves suppression of NF-kappa-B.

1. Minty, A. et al. (1993) Nature 362, 248-50. PMID: 8096327

2. McKenzie, AN. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 3735-9. PMID: 8097324

3. Defrance, T. et al. (1994) The Journal of experimental medicine 179, 135-43. PMID: 7903680

4. Luttmann, W. et al. (1996) Journal of immunology (Baltimore, Md. : 1950) 157, 1678-83. PMID: 8759755

5. Schnyder, B. et al. (1996) Blood 87, 4286-95. PMID: 8639787

6. Miloux, B. et al. (1997) FEBS letters 401, 163-6. PMID: 9013879

7. Kasaian, MT. et al. (2011) Journal of immunology (Baltimore, Md. : 1950) 187, 561-9. PMID: 21622864

Nota

For research use only.

Isotype Control

Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)

Imágenes

Bioactivity

SEC-HPLC detection for Anti-Human IL13 Antibody (ABS1981).
SDS-PAGE

SDS-PAGE for Anti-Human IL13 Antibody (SAA2016).
Western blot

Western blot analysis was performed using anti-IL13 monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant human IL13 (Catalog No: HW632012), 50ng
Lane 2: recombinant human IL13 (Catalog No: HW632012), 30ng
Lane 3: recombinant human IL13 (Catalog No: HW632012), 20ng