Anti-Human IL-13 Recombinant Antibody (SAA2016) (HW632013)

Name: Anti-Human IL-13 Recombinant Antibody (SAA2016)
Brand: abinScience
SKU: HW632013
Price: 110 USD
Availability: InStock

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Spécification :

20ug
50ug
100ug
1mg

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HW632013

Reactivité des espèces

Human

Applications

ELISA, WB

Espèce hôte

Human

Clonalité

Monoclonal

Isotype

IgG4, kappa

ID de clone

SAA2016

Applications testées

Cible

IL-13, IL13, Interleukin-13, NC30

Niveau d'endotoxines

< 10 EU/mg

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P35225

RRID

Anti-Human IL13 Antibody (SAA2016) (abinScience Cat# HW632013, RRID:AB_3727928)
_x005F_x000D_

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Interleukin-13 (IL13) is a ~15 kDa protein. Cytokine that plays important roles in allergic inflammation and immune response to parasite infection. Synergizes with IL2 in regulating interferon-gamma synthesis. Stimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells. Plays an important role in controlling IL33 activity by modulating the production of transmembrane and soluble forms of interleukin-1 receptor-like 1/IL1RL1. Displays the capacity to antagonize Th1-driven proinflammatory immune response and downregulates synthesis of many proinflammatory cytokines including IL1, IL6, IL10, IL12 and TNF through a mechanism that partially involves suppression of NF-kappa-B.

1. Minty, A. et al. (1993) Nature 362, 248-50. PMID: 8096327

2. McKenzie, AN. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 3735-9. PMID: 8097324

3. Defrance, T. et al. (1994) The Journal of experimental medicine 179, 135-43. PMID: 7903680

4. Luttmann, W. et al. (1996) Journal of immunology (Baltimore, Md. : 1950) 157, 1678-83. PMID: 8759755

5. Schnyder, B. et al. (1996) Blood 87, 4286-95. PMID: 8639787

6. Miloux, B. et al. (1997) FEBS letters 401, 163-6. PMID: 9013879

7. Kasaian, MT. et al. (2011) Journal of immunology (Baltimore, Md. : 1950) 187, 561-9. PMID: 21622864

Note

For research use only.

Isotype Control

Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)

Images

Bioactivity

SEC-HPLC detection for Anti-Human IL13 Antibody (ABS1981).
SDS-PAGE

SDS-PAGE for Anti-Human IL13 Antibody (SAA2016).
Western blot

Western blot analysis was performed using anti-IL13 monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant human IL13 (Catalog No: HW632012), 50ng
Lane 2: recombinant human IL13 (Catalog No: HW632012), 30ng
Lane 3: recombinant human IL13 (Catalog No: HW632012), 20ng