

| Número de catálogo | HV492013 | ||||
|---|---|---|---|---|---|
| Reactividad de especies | Human | ||||
| Aplicaciones | ELISA | ||||
| Especie huésped | Mouse | ||||
| Clonalidad | Monoclonal | ||||
| Isotipo | IgG2a, kappa | ||||
| ID de clon | SAA1626 | ||||
| Objetivo | Melanoma differentiation-associated protein-like protein, Interleukin-19, IL-19, IL19, NG.1, ZMDA1 | ||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||
| Pureza | >95% as determined by SDS-PAGE. | ||||
| Purificación | Protein A/G purified from cell culture supernatant. | ||||
| Número de acceso | Q9UHD0 | ||||
| RRID | Anti-Human IL19 Antibody (SAA1626) (abinScience Cat# HV492013, RRID:AB_3727387) |
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| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Fondo | Interleukin-19 (IL19) is a ~20 kDa protein. Cytokine that functions as an anti-inflammatory and proangiogenic factor. Polarizes adaptive immunity to an anti-inflammatory phenotype through induction of T-helper 2 responses by both down-regulation of IFN-gamma and up-regulation of IL4 and IL13. Produced by osteocytes, stimulates granulopoiesis and neutrophil formation. Exerts its biological effect through a receptor complex consisting of a heterodimer of IL20RA and IL20RB. In turn, activates the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, and importantly, STAT3. 1. Small, SH. et al. (2021) Science signaling 14, eaba2611. PMID: 34932373 2. Oral, HB. et al. (2006) European journal of immunology 36, 380-8. PMID: 16365913 3. Parrish-Novak, J. et al. (2002) The Journal of biological chemistry 277, 47517-23. PMID: 12351624 4. Dumoutier, L. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 3545-9. PMID: 11564763 | ||||
| Nota | For research use only. |

SDS-PAGE for Anti-Human IL19 Antibody (SAA1626)
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