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Anti-Human IL-21 Recombinant Antibody (SAA0390), APC (HV658137)

Anti-Human IL-21 Recombinant Antibody (SAA0390), APC
Anti-Human IL-21 Recombinant Antibody (SAA0390), APC
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概要
カタログ番号HV658137
種反応性Human
アプリケーションELISA, FCM
宿主種Mouse
クローン性Monoclonal
アイソタイプIgG1, kappa
クローンIDSAA0390
抱合APC
テスト済みアプリケーション FCM
ターゲット IL-21, Interleukin-21, IL21, Za11
エンドトキシンレベル Please contact with the lab for this information.
関連製品 Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC
アクセッション番号 Q9HBE4
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Store at 4°C for 12 months. Protect from light. Do not freeze.
背景

Interleukin-21 (IL21) is a ~18 kDa protein. Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells. Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection.

1. Parrish-Novak, J. et al. (2000) Nature 408, 57-63. PMID: 11081504
2. Strengell, M. et al. (2004) Journal of leukocyte biology 76, 416-22. PMID: 15178704
注意事項 For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
イメージ
  • Anti-Human IL-21 Recombinant Antibody (SAA0390), APC

    Flow CytoMetry

    Flow-cytometry using APC anti-human IL21 antibody. Hela cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an APC anti-human IL21 monoclonal antibody (Catalog: HV658137, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

参考文献
Formula
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