Anti-Human IL28B/IL28C/IFNL3 Recombinant Antibody (SAA0394), APC (HV083137)

Name: Anti-Human IL28B/IL28C/IFNL3 Recombinant Antibody (SAA0394), APC
Brand: abinScience
SKU: HV083137
Price: 256 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HV083137
Reactivité des espèces	Human
Applications	ELISA, FCM
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG2a, kappa
ID de clone	SAA0394
Conjugaison	APC
Cible	IFNL3, IL28B, Interferon lambda-3, IL28C, IFN-lambda-3, Interleukin-28B, Interleukin-28C, Cytokine Zcyto22, IL-28B, ZCYTO22, IL-28C
Niveau d'endotoxines	Please contact with the lab for this information.
Produits associés	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), APC
Numéro d'accès	Q8IZI9
Forme	Liquid
Tampon de stockage	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte	Interferon lambda-3 (IL28B/IL28C) is a ~21 kDa protein. Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense.
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human IL28B/IL28C/IFNL3 Recombinant Antibody (SAA0394), APC.pdf

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