Anti-Human IL28B/IL28C/IFNL3 Recombinant Antibody (SAA0394), APC (HV083137)

Name: Anti-Human IL28B/IL28C/IFNL3 Recombinant Antibody (SAA0394), APC
Brand: abinScience
SKU: HV083137
Price: 256 USD
Availability: InStock

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Каталожный номер	HV083137
Реактивность видов	Human
Применения	ELISA, FCM
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	IgG2a, kappa
ID клона	SAA0394
Конъюгация	APC
Цель	IFNL3, IL28B, Interferon lambda-3, IL28C, IFN-lambda-3, Interleukin-28B, Interleukin-28C, Cytokine Zcyto22, IL-28B, ZCYTO22, IL-28C
Уровень эндотоксинов	Please contact with the lab for this information.
Связанные продукты	Mouse IgG2a, kappa Recombinant Isotype Control Antibody (MOPC-173), APC
Номер доступа	Q8IZI9
Форма	Liquid
Буфер хранения	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Store at 4°C for 12 months. Protect from light. Do not freeze.
Фон	Interferon lambda-3 (IL28B/IL28C) is a ~21 kDa protein. Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense.
Примечание	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human IL28B/IL28C/IFNL3 Recombinant Antibody (SAA0394), APC.pdf

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