Anti-Human IL-31RA Recombinant Antibody (SAA0825), PE (HV121127)

Name: Anti-Human IL-31RA Recombinant Antibody (SAA0825), PE
Brand: abinScience
SKU: HV121127
Price: 290 USD
Availability: InStock

Datasheet Compartir producto Copiar información

Precio(USD):

Especificación:

50T
100T

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo	HV121127
Reactividad de especies	Human
Aplicaciones	ELISA, FCM
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	IgG2, kappa
ID de clon	SAA0825
Conjugación	PE
Aplicaciones probadas	FCM
Objetivo	IL-31RA, Interleukin-31 receptor subunit alpha, IL31RA, hGLM-R, ZcytoR17, IL-31R-alpha, GPL, CRL3, Cytokine receptor-like 3, IL-31R subunit alpha, IL-31 receptor subunit alpha, Gp130-like receptor, GLM-R, Gp130-like monocyte receptor
Nivel de endotoxinas	Please contact with the lab for this information.
Productos asociados	Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10), PE
Número de acceso	Q8NI17
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo	Interleukin-31 receptor subunit alpha (IL31RA) is a ~82 kDa protein. Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro. _x005F_x000D_ _x005F_x000D_ 1. Ghilardi, N. et al. (2002) The Journal of biological chemistry 277, 16831-6. PMID: 11877449 _x005F_x000D_ _x005F_x000D_ 2. Diveu, C. et al. (2003) The Journal of biological chemistry 278, 49850-9. PMID: 14504285 _x005F_x000D_ _x005F_x000D_ 3. Dreuw, A. et al. (2004) The Journal of biological chemistry 279, 36112-20. PMID: 15194700 _x005F_x000D_ _x005F_x000D_ 4. Diveu, C. et al. (2004) European cytokine network 15, 291-302. PMID: 15627637 _x005F_x000D_ _x005F_x000D_ 5. Dillon, SR. et al. (2004) Nature immunology 5, 752-60. PMID: 15184896
Nota	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

Imágenes

Flow CytoMetry

Flow-cytometry using PE anti-human IL31RA antibody. U87 cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human IL31RA monoclonal antibody (Catalog: HV121127, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

Referencias

Datasheet